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The Titan submersible suffered a catastrophic implosion that likely killed its pilot and four passengers instantly amid the intense water pressure in the deep North Atlantic, experts said.

WASHINGTON (AP) — The first gene therapy for a deadly form of muscular dystrophy received preliminary U.S. approval on Thursday despite concerns from some government scientists about the treatment’s ability to help boys with the inherited disease.

WASHINGTON (AP) — America’s honeybee hives just staggered through the second highest death rate on record, with beekeepers losing nearly half of their managed colonies, an annual bee survey found.

WASHINGTON (AP) — A powerful animal sedative in the illicit drug supply is complicating the U.S. response to the opioid crisis, scrambling longstanding methods for reversing overdoses and treating addiction.

Talk to someone who rode on the Titan submersible, and they’re likely to mention a technological glitch: the propulsion system failed or communications with people on the surface cut out. Maybe there were problems balancing weights on board.

The wrecks of the Titanic and the Titan sit on the ocean floor, separated by 1,600 feet (490 meters) and 111 years of history. How they came together unfolded over an intense week that raised temporary hopes and left lingering questions.

One year ago Saturday, the U.S. Supreme Court rescinded a five-decade-old right to abortion, prompting a seismic shift in debates about politics, values, freedom and fairness.

In the year since the U.S. Supreme Court issued its ruling in Dobbs v. Jackson Women’s Health Organization that ended nearly a half-century of a nationwide right to abortion, states have enacted contrasting policies on the issue. The Dobbs decision overturned the 1973 Roe v. Wade ruling that protected the right to an abortion until fetal viability, which is generally considered to be around 23 or 24 weeks of pregnancy.

NEW CUMBERLAND, W.Va. (AP) — A producer of industrial gas in West Virginia has agreed to pay $1.9 million to settle allegations that it violated the Clean Water Act by dumping copper, aluminum, residual chlorine, iron and phenolics into the Ohio River at levels above what was permitted, federal regulators said Friday.

NORFOLK, Va. (AP) — When the Titan submersible made its fateful dive into the North Atlantic on Sunday, it also plunged into the murkily regulated waters of deep-sea exploration.